January 22, 2026 · 6 min read
What is GHK-Cu? The Copper Peptide Research Guide
GHK-Cu is a copper-binding tripeptide with a striking effect on gene expression, collagen and hair follicle research.
What is GHK-Cu?
GHK-Cu is a naturally occurring tripeptide, Glycyl-L-histidyl-L-lysine, chelated to copper(II). Discovered in human plasma in the 1970s, it has been extensively studied for its effects on dermal remodeling, hair follicle biology and antioxidant defense.
How GHK-Cu works
GHK-Cu modulates expression of thousands of human genes — including those involved in collagen and elastin synthesis, DNA repair and antioxidant enzyme activity. Copper delivery through the tripeptide carrier supports SOD activity and metalloproteinase modulation.
Research applications
GHK-Cu is a staple in dermal remodeling studies, ex-vivo scalp research and antioxidant assays. It also appears in Peptana's GLOW blend alongside BPC-157 and TB-500 for combined tissue-repair protocols.
Featured research peptide
GHK-Cu — 100 mg
GHK-Cu is a naturally occurring copper-binding tripeptide. It is widely studied in dermatological and cosmetic research for skin regeneration, collagen activity, and antioxidative profiles.